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Archives of recent messages from Leprosy Mailing List (LML) managed by Dr Salvatore Noto.

Over the past few years, LML moderated by Dr Noto has become one of the most important online resource for promoting discussions about leprosy.

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Leprosy Mailing List – December 13th, 2007

 

Ref.:     Dapsone it is not a medication that is considered typical for use for vitiligo

From:   James J. Nordlund, Cincinnati, USA


 

  

Dear Dr. Salafia,

 

Dapsone, a medication I have used many times for various disorders, is not a standard medication used to treat patients with vitiligo.  I have read many reviews and it is not a medication that is considered typical for use for vitiligo.  

 

Some of the comments you make are correct.  Dapsone does cause hemolysis but that has no known relevance to vitiligo.  Pheomelanins are not white melanins but are orange red color. That is what the word “pheo-“ means, orange red.  Patients with vitiligo have neither pheomelanin or eumelanin in the white skin because there are no melanocytes in the white skin.

 

I have not read your article  in the Italian journal or your book but would like to have the opportunity to do so.  I am quite willing to look at the data and change my opinion if your data are sufficient.  Please send me a copy if possible of whatever data you have collected.

 

Yours sincerely,

 

James J. Nordlund, MD

 

 

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