Leprosy
Mailing List, July 3rd, 2009
Ref.:
Dapsone
related complications: hypersensitivity and toxicity.
From:
Dhakal
K. P.,
Kathmandu
,
Nepal
Dear Ariyawansa,
Thank
you very much for your message (LML June 22nd, 2009).
The
case presented by you is almost definitely the case of dapsone related
complication. You have
not mentioned about pruritus and relevant skin presentations which are
the commonest presentations of dapsone hypersensitivity which ranges
from mild pruritus with some skin rashes to severe exfoliative
dermatitis. I have
successfully treated many cases of dapsone hypersensitivity with
somewhat similar presentation like your case but with associated with
skin manifestations and pruritus. In
this case presented by you, it seems to be dapsone toxicity which is
very different from hypersensitivity reaction. In the case
presented by you, there is high chance of dapsone related
complication but at the same time we can look for any other
accompanying pathology.
Dr
K P Dhakal
NLR
Kathmandu
,
Nepal
