Leprosy
Mailing List, January 11th, 2009
Ref.: Orfloxacin as
alternative drug in dapsone hypersensitive paucibacillary (PB) leprosy
patients?
From:
Kamaladasa S. D.,
Nugegoda
,
Sri Lanka
Dear Dr Noto,
I would like
to know the dosage and the duration of treatment with Orfloxacin for
leprosy patients who are having sensitivity reaction to Dapsone?
If we start
them on Orfloxacin 400 mg bd for 6 months plus monthly Rifampicin 600
mg would that be enough for PB therapy?
The drug
literature form in the pack of course does not mention about Mycobacterium
leprae as one of the sensitive organisms and also it says it
should be taken 400 mg daily not exceeding 2 months duration.
Could you
please let me know about the efficacy of this drug in treating
leprosy, the dosage, the duration of the treatment and also reported
complications of long term therapy?
I would greatly value your
opinion.
Thanks
Dr S. D. Kamaladasa
Consultant Dermatologist
University
of
Sri Jayawardenapura
Nugegoda
,
Sri Lanka
.
