Leprosy
Mailing List – November 3rd, 2010
Ref.: Rifampicin,
ofloxacin and minocycline (ROM) in leprosy
From:
Frankel Richard I.,
Hawai'i, USA
Dear
Salvatore and Dr Ahmad,
I
refer to Dr Ahmad’s message dated LML Nov. 2nd, 2010. Three
pertinent references are:
Single-Lesion
Multicentre Trial Group. Efficacy
of single-dose multidrug therapy for the treatment of single-lesion
paucibacillary leprosy. Indian
J. Lepr. 69:121-129
(1997)
Revankar,
C.R., Bulchand, H.O., Pai, V.V., et
al. Relapse rate in
paucibacillary leprosy treated with single dose.
Int. J. Lepr. 69:S131
(2001)
Lockwood,
D. N. J. Rifampicin/Minocycline and ofloxacin for single
lesions—what is the evidence? Lepr
Rev 68:299-300 (1997)
This
treatment is discussed briefly in the chapter on Leprosy by Dr.
Scollard and myself in the Fourth Edition of "Bacterial
Infections of Humans", edited by Drs. Brachman and Abrutyn,
published by Springer in 2009.
Sincerely,
Richard
I. Frankel, M.D., M.P.H., F.A.C.P.
Emeritus
Professor of Medicine
University
of
Hawai'i
