Leprosy
Mailing List – May 9th , 2010
Ref.: Small
child MDT - please advise
From: Saba
Lambert,
Addis Ababa
,
Ethiopia
Dear
LML members,
I
would be grateful if you could advice me on a case I have come across
at
ALERT
Hospital
in
Addis Ababa
,
Ethiopia
.
The
patient is a 2 year old child, weight 9kg, brought it for a check up
by family. The father was
diagnosed as a lepromatous case 7 months ago at our clinic with
BI: 5,5,5. He is on his 7th month of MDT. They
live in a rural environment about 8 hours travel from Addis.
The
child was found to have a few nodules on the face, arms and buttocks. Her
BI is 3,2,1.
The
problem I have is with the treatment to give her. We
have no low does medication in
Ethiopia
and depend on the WHO packs of MDT (adult and child 10-14).
For her 9kg she would need a monthly dose of Rifampicin 150mg,
Clofazimine 25 mg and Dapsone 25mg, and a daily dose of dapsone 25mg
and every other day dose of clofazimine 25mg. Form the child MDT
pack, we have Rifampicin 150mg available but the dapsone and
clofazimine come only in 50 mg tablets and blisters respectively.
Would
you have any suggestions of how I can adjust her treatment?
I
am grateful for you suggestions.
Dr
Saba Lambert
Dr
Saba Lambert
Clinical
Research Fellow
Clinical
Research Unit
Department
of Infectious and Tropical Diseases
London
School
of
Hygiene and Tropical Medicine
Room
251,
Keppel Street
London
WC1E
7HT
Tel:
44 207 6127863 or 44 7921 266473
