Leprosy
Mailing List – September 22nd, 2010
Ref.: Clofazimine
in ENL
From:
Willem
Theuvenet, Apeldoorn, The Netherlands
Dear
Salvatore,
In
addition to the valuable comments of Pieter Schreuders and Ben Naafs (LML
Sept. 2nd 2010): I fully agree on their comments. Perhaps
a word of caution in those cases of chronic recurrent ENL when a
prolonged regime of Clofazamine needs to be combined
with corticosteroids. In
that situation there is definitely an increased risk of drug induced
gastro-intestinal bleeding. This
risk is further increased when analgetics are added.
These
patients should be carefully monitored for this potential life
threatening complication.
With
best regards,
Willem
Theuvenet
